Quick Overview for Sema4a Protein (His tag) (ABIN7320641)
抗原
See all Sema4a 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Sema4a protein is labelled with His tag.
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原理
- Recombinant Mouse Semaphorin-4A/SEMA4A Protein (His Tag)
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序列
- Thr33-His682
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产品特性
- Recombinant Mouse Semaphorin 4A is produced by our Mammalian expression system and the target gene encoding Thr33-His682 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a) (AA 1-761) protein (GST tag)
Sema4a 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a) (AA 33-132) protein (GST tag)Sema4a 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a) (AA 33-683) protein (His tag)Sema4a 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Sema4a (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
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别名
- Semaphorin-4A/SEMA4A
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背景
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Background: Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A promotes phosphorylation of TIMD2, inhibits angiogenesis, and promotes axon growth cone collapse, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Synonym: Semaphorin-4A,Semaphorin-B,Sema B,Sema4a,Semab, SemB
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分子量
- 72.7 kDa
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UniProt
- Q62178
抗原
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