S100A9 蛋白
Quick Overview for S100A9 蛋白 (ABIN7317642)
抗原
See all S100A9 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human S100A9 Protein (Active)
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序列
- Met 1-Pro 114
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产品特性
- A DNA sequence encoding the native form of human S100A9 (NP_002956.1) (Met 1-Pro 114) was expressed.
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Biological Activity Comment
- This product displays no activity in cell-based assay.
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S100 Calcium Binding Protein A9 (S100A9) (AA 2-114) protein (His tag)
S100A9 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
S100 Calcium Binding Protein A9 (S100A9) (AA 1-130) protein (His tag)S100A9 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
S100 Calcium Binding Protein A9 (S100A9) (AA 1-114) protein (GST tag)S100A9 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A9 (S100A9) (AA 1-114) protein (His tag)S100A9 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
S100 Calcium Binding Protein A9 (S100A9) (AA 2-113) protein (His tag)S100A9 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
S100 Calcium Binding Protein A9 (S100A9) (AA 1-114) protein (His-IF2DI Tag)S100A9 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
S100 Calcium Binding Protein A9 (S100A9) protein (Fc Tag)S100A9 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
S100 Calcium Binding Protein A9 (S100A9) protein (Myc-DYKDDDDK Tag)S100A9 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
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别名
- S100A9
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背景
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Background: S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100 % soluble in ammonium sulfate at neutral pH . Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calcium-binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
Synonym: 60B8AG,CAGB,CFAG,CGLB,L1AG,LIAG,MAC387,MIF,MRP-14,MRP14,NIF,P14
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NCBI登录号
- NP_002956
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途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
抗原
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