S100A12 蛋白
This Recombinant S100A12 protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN7317645
发货至:
中国
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Quick Overview for S100A12 蛋白 (ABIN7317645)
抗原
See all S100A12 蛋白
S100A12
(S100 Calcium Binding Protein A12 (S100A12))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
ELISA
纯度
> 98 % as determined by reducing SDS-PAGE.
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原理
- Recombinant Human S100A12/CAGC Protein
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序列
- Met 1-Glu 92
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产品特性
- A DNA sequence encoding the native human S100A12 (NP_005612.1) (Met 1-Glu 92) was expressed.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Immobilized recombinant human S100A12 at 2 μg/ml (100 μl/well) can bind human AGER with a linear range of 0.032-20 μg/ml.
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S100 Calcium Binding Protein A12 (S100A12) (AA 2-92) protein (His-IF2DI Tag)
S100A12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) protein (GST tag)S100A12 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
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别名
- S100A12/CAGC
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背景
- CGRP,Calcitermin,Calcium-binding protein in amniotic fluid 1,Calgranulin-C,EN-RAGE,Extracellular newly identified RAGE-binding protein,MRP-6,Migration inhibitory factor-related protein 6,Protein S100-A12,S100 calcium-binding protein A12,S100A12,S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is100 % soluble in ammonium sulfateat neutral pH . Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A12, also known as S100 calcium-binding protein A12, Calcium-binding protein in amniotic fluid 1, Calgranulin-C, and S100A12, is a member of the S-101 family. Like the majority of S100 proteins, S100A12 is a dimer, with the interface between the two subunits being composed mostly of hydrophobic residues. The fold of S100A12 is similar to the other known crystal and solution structures of S100 proteins, except for the linker region between the two EF-hand motifs. S100A12 plays an important role in the inflammatory response.
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分子量
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Calculated MW: 10.6 kDa
Observed MW: 10 kDa
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基因ID
- 6283
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NCBI登录号
- NP_005612
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UniProt
- P80511
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途径
- Toll-Like Receptors Cascades, S100 Proteins
抗原
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