PROS1 Protein (His tag)
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Quick Overview for PROS1 Protein (His tag) (ABIN7197584)
抗原
See all PROS1 (PROS) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This PROS1 protein is labelled with His tag.
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原理
- Recombinant Human PROS1/Protein S Protein (His Tag)
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序列
- Met 1-Ser676
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产品特性
- A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- PROS1 (PROS) (Protein S (PROS))
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别名
- PROS1
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背景
- PROS,PS21,PS22,PS23,PS24,PS25,PSA,Protein S,THPH5,THPH6,PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
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分子量
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Calculated MW: 74.1 kDa
Observed MW: 69-89 kDa
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基因ID
- 5627
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UniProt
- P07225
抗原
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