Pleiotrophin Protein (PTN) (His tag)
Quick Overview for Pleiotrophin Protein (PTN) (His tag) (ABIN7320789)
抗原
See all Pleiotrophin (PTN) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Pleiotrophin protein is labelled with His tag.
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原理
- Recombinant Mouse Pleiotrophin/PTN/HB-GAM Protein (His Tag)
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序列
- Gly33-Asp168
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产品特性
- Recombinant Mouse Pleiotrophin is produced by our Mammalian expression system and the target gene encoding Gly33-Asp168 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)
PTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Pleiotrophin (PTN) (AA 1-168) protein (GST tag)PTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pleiotrophin (PTN) (Active) proteinPTN 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)PTN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Pleiotrophin (PTN)
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别名
- Pleiotrophin/PTN/HB-GAM
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背景
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Background: Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50 % amino acid (aa) sequence identity, share some functions, and constitute a family. PTN is a highly conserved protein? human, mouse, rat, canine, porcine, equine and bovine PTN share 98 % aa sequence identity orgreater. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated withneuronal development or stresses such as brain ischemia and Parkinson's disease.
Synonym: Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Osteoblast-specific factor 1, OSF-1,HARP,HB-GAM,HBBN,HBNF,OSF,Osf-1,Osf1
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分子量
- 16.1 kDa
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UniProt
- P63089
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途径
- RTK signaling
抗原
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