PGLYRP1 Protein (His tag)
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- 抗原 See all PGLYRP1 蛋白
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This PGLYRP1 protein is labelled with His tag.
- 原理
- Recombinant Mouse PGLYRP1/PGRP-S Protein (His Tag)
- 序列
- Met 1-Glu 182
- 产品特性
- A DNA sequence encoding the mouse PGLYRP (O88593) (Met 1-Glu 182) was expressed, with a C-terminal polyhistidine tag
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product PGLYRP1 蛋白
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Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 19-182) protein (Fc Tag)
PGLYRP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 22-196) protein (Fc Tag)PGLYRP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 138-196) protein (GST tag)PGLYRP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 1-196) protein (GST tag)PGLYRP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 22-196) protein (His tag)PGLYRP1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from PBS, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- 别名
- PGLYRP1/PGRP-S (PGLYRP1 产品)
- 背景
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Background: Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. It has bactericidal activity towards Gram-positive bacteria. PGLYRP1 / PGLYRP may kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. It binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Peptidoglycan recognition proteins ( PGRPs or PGLYRPs ) are innate immunity proteins that are conserved from insects to mammals, recognize bacterial peptidoglycan, and function in antibacterial immunity and inflammation. Mammals have four PGRPs: PGLYRP1, PGLYRP2, PGLYRP3, and PGLYRP4. They are secreted proteins expressed in polymorphonuclear leukocytes ( PGLYRP1 ), liver ( PGLYRP2 ), or on body surfaces, mucous membranes, and in secretions (saliva, sweat) (PGLYRP3 and PGLYRP4). All PGRPs recognize bacterial peptidoglycan. The PGRPs likely play a role both in antibacterial defenses and several inflammatory diseases. They modulate local inflammatory responses in tissues (such as arthritic joints) and there is evidence for association of PGRPs with inflammatory diseases, such as psoriasis.
Synonym: Pglyrp;PGRP;PGRP-S;Tag7;Tasg7;Tnfsf3l
- 分子量
- 20.2 kDa
- UniProt
- O88593
- 途径
- Activation of Innate immune Response
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