PON3 Protein (His tag)
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Quick Overview for PON3 Protein (His tag) (ABIN7317316)
抗原
See all PON3 蛋白蛋白类型
宿主
资源
纯度
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标记
- This PON3 protein is labelled with His tag.
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原理
- Recombinant Human PON3/Paraoxonase 3 Protein (50 Ser/Asn, His Tag)
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序列
- Met 1-Leu 354
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产品特性
- A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 1 mM CaCL2, 10 % glycerol, 0.1 % DDM
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- PON3 (Paraoxonase 3 (PON3))
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别名
- PON3/Paraoxonase 3
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背景
- PON3,KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
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分子量
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Calculated MW: 42 kDa
Observed MW: 45 kDa
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基因ID
- 5446
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UniProt
- Q15166
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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