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Oncomodulin Protein (OCM) (His tag)

This Recombinant Oncomodulin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318847
发货至: 中国
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Quick Overview for Oncomodulin Protein (OCM) (His tag) (ABIN7318847)

抗原

See all Oncomodulin (OCM) 蛋白
Oncomodulin (OCM)

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This Oncomodulin protein is labelled with His tag.

    原理

    Recombinant Human Oncomodulin-1/OCM Protein (His Tag)

    序列

    Met 1-Ser109

    产品特性

    Recombinant Human Oncomodulin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ser109 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 7.5.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Oncomodulin (OCM)

    别名

    Oncomodulin-1/OCM

    背景

    Background: Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.

    Synonym: Oncomodulin-1, OM, Parvalbumin Beta, OCM, OCM1, OCMN

    分子量

    14.3 kDa

    UniProt

    P0CE72
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