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MGMT Protein (His tag)

This Recombinant MGMT protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318122
发货至: 中国
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Quick Overview for MGMT Protein (His tag) (ABIN7318122)

抗原

See all MGMT 蛋白
MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

蛋白类型

Recombinant

宿主

  • 8
  • 2
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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This MGMT protein is labelled with His tag.

    原理

    Recombinant Human MGMT Protein (His Tag)

    序列

    Met 1-Asn207

    产品特性

    Recombinant Human Methylated-DNA--protein-cysteine methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asn207 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mMTrisHCl,1 mM EDTA, pH 8.0 .

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

    别名

    MGMT

    背景

    Background: MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-methyl-L-cysteine.

    Synonym: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNAmethyltransferase,O-6-methylguanine-DNA-alkyltransferase, MGMT

    分子量

    23.8 kDa

    UniProt

    P16455

    途径

    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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