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Quick Overview for Notch1 Protein (His tag) (ABIN7320796)
抗原
See all Notch1 (NOTCH1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Notch1 protein is labelled with His tag.
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原理
- Recombinant Mouse Motch A/NOTCH1 Protein (His Tag)
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序列
- Ala18-Gln526
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产品特性
- Recombinant Mouse Notch 1 is produced by our Mammalian expression system and the target gene encoding Ala18-Gln526 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Notch 1 (NOTCH1) (AA 19-526) protein (His-Avi Tag)
NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 1 (NOTCH1) (AA 19-526) protein (His-Avi Tag,Biotin)NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 1 (NOTCH1) (AA 2309-2555) protein (His tag)NOTCH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Notch 1 (NOTCH1) (Active) protein (His tag)NOTCH1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 82 % as determined by SDS-PAGE Active
Notch 1 (NOTCH1) (AA 23-132) protein (GST tag)NOTCH1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (His tag)NOTCH1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (Fc Tag)NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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别名
- Motch A/NOTCH1
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背景
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Background: Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain and a PEST sequence. Notch1 may play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation and may be involved in mesoderm development, somite formation and neurogenesis.
Synonym: Neurogenic locus notch homolog protein 1, Notch 1, Motch A, Mt14,lin-12,Mis6,N1,Tan1
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分子量
- 54.4 kDa
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UniProt
- Q01705
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途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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