Neurotrophin 3 Protein (NTF3)
Quick Overview for Neurotrophin 3 Protein (NTF3) (ABIN7318822)
抗原
See all Neurotrophin 3 (NTF3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human Neurotrophin-3/NTF3 Protein (Active)
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序列
- Tyr139-Thr 257
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产品特性
- Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized Human NT-3 at 10ug/ml(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Neurotrophin 3 (NTF3)
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别名
- Neurotrophin-3/NTF3
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背景
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Background: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.
Synonym: Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
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分子量
- 13.6 kDa
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UniProt
- P20783
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途径
- RTK signaling, Neurotrophin Signaling Pathway
抗原
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