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Neurotrophin 3 Protein (NTF3)

This Recombinant Neurotrophin 3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318822
发货至: 中国

Quick Overview for Neurotrophin 3 Protein (NTF3) (ABIN7318822)

抗原

See all Neurotrophin 3 (NTF3) 蛋白
Neurotrophin 3 (NTF3)

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

  • 19
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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Neurotrophin-3/NTF3 Protein (Active)

    序列

    Tyr139-Thr 257

    产品特性

    Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Human NT-3 at 10ug/ml(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Neurotrophin 3 (NTF3)

    别名

    Neurotrophin-3/NTF3

    背景

    Background: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

    Synonym: Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3

    分子量

    13.6 kDa

    UniProt

    P20783

    途径

    RTK signaling, Neurotrophin Signaling Pathway
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