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- 抗原 See all NBL1 蛋白
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This NBL1 protein is labelled with His tag.
- 原理
- Recombinant Mouse NBL1/DAND1 Protein (His Tag)
- 序列
- Ala17-Asp178
- 产品特性
- Recombinant Mouse Differential Screening-selected Gene Aberrant in Neuroblastoma is produced by our Mammalian expression system and the target gene encoding Ala17-Asp178 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-181) protein (His-IF2DI Tag)
NBL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 1-180) protein (GST tag)NBL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NBL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- 别名
- NBL1/DAND1 (NBL1 产品)
- 背景
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Background: Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of the DAN family of secreted glycoproteins. DAN family antagonists are characterized by a DAN domain that contains a cystine knot motif which is essential for binding to BMP ligands. Members of this family include DAN, gremlin, protein related to DAN and cerberus (PRDC), cerberus, sclerostin (SOST) and uterine sensitization-associated gene 1 protein, and control diverse processes in growth, development and the cell cycle. It has also been reported that DAN family plays crucial role in early mouse embryo development by inhibiting the action of bone morphogenic proteins and modulating the action of transforming growth factor-β superfamily members. DAN is synthesized by small-to intermediate-sized DRG neurons and transported to the sensory nerve terminals in the skin or to the sensory nerve terminals in the dorsal horn. It has been reported that DAN is ubiquitously expressed in adult rat and human tissues. Morphological studies have revealed that, in adult rat, DAN mRNA is expressed ubiquitously in lung and brain, but not in liver.
Synonym: DAND1, NBL1, DAN domain family member 1, neuroblastoma suppressor of tumorigenicity 1, Protein N03, suppression of tumorigenicity 1,DAN,Dana
- 分子量
- 18.4 kDa
- UniProt
- Q61477
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