Neurexin 3 Protein (NRXN3) (His tag)
This Recombinant Neurexin 3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7317470
发货至:
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Quick Overview for Neurexin 3 Protein (NRXN3) (His tag) (ABIN7317470)
抗原
See all Neurexin 3 (NRXN3) 蛋白
Neurexin 3 (NRXN3)
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 94 % as determined by reducing SDS-PAGE.
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标记
- This Neurexin 3 protein is labelled with His tag.
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原理
- Recombinant Human NRXN3 Protein (His Tag)
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序列
- Met 1-Thr 357
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产品特性
- A DNA sequence encoding the human NRXN3 beta isoform 2 (NP_620426.2) extracellular domain (Met 1-Thr 357) was expressed, with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Neurexin 3 (NRXN3) (AA 101-210) protein (GST tag)
NRXN3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neurexin 3 (NRXN3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NRXN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Neurexin 3 (NRXN3)
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别名
- NRXN3
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背景
- C14orf60,Neurexin-3-beta, also known as Neurexin III-beta and NRXN3, is a single-pass type I membrane protein which belongs to theneurexin family. It contains onelaminin G-like domain. It is a neuronal cell surface protein that may be involved in cell recognition and cell adhesion. Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two, NRXN1 and NRXN3, are among the largest known human genes. Three of the genes ( NRXN1, NRXN2, NRXN3 ) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms, a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain EGF-like sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. NRXN3 have been linked to genetic predisposition towards a number of conditions such as alcohol or drug addiction, or obesity.
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分子量
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Calculated MW: 36.0 kDa
Observed MW: 50-60 kDa
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基因ID
- 9369
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NCBI登录号
- NP_620426
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UniProt
- Q9HDB5
抗原
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