MAX Protein (His-GST)
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Quick Overview for MAX Protein (His-GST) (ABIN7317333)
抗原
See all MAX 蛋白蛋白类型
宿主
资源
纯度
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标记
- This MAX protein is labelled with His-GST.
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原理
- Recombinant Human MAX Protein (His &GST Tag)
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序列
- Met 1-Ser160
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产品特性
- A DNA sequence encoding the human MAX (NP_002373) (Met1-Ser160) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- MAX (MYC Associated Factor X (MAX))
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别名
- MAX
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背景
- BHLHD4,Class D Basic Helix-Loop-Helix Protein 4,MAX,Myc-Associated Factor X,Protein Max,bHLHd4,MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to MAX family. It is highly expressed in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. MYC associated factor X may also repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Multiple alternatively spliced transcript variants have been described for MYC associated factor X gene but the full-length nature for some of them is unknown.
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分子量
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Calculated MW: 46.1 kDa
Observed MW: 73 kDa
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基因ID
- 4149
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NCBI登录号
- NP_002373
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UniProt
- P61244
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途径
- Mitotic G1-G1/S Phases
抗原
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