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METTL11A 蛋白

METTL11A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317612
发货至: 中国
  • 抗原 See all METTL11A 蛋白
    METTL11A (Methyltransferase Like 11A (METTL11A))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human METTL11A Protein
    序列
    Thr 2-Arg 223
    产品特性
    A DNA sequence encoding the human METTL11A (NP_054783.2) (Thr 2-Arg 223) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product METTL11A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 150 mM NaCl, 10 % glycerol, pH 7.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    METTL11A (Methyltransferase Like 11A (METTL11A))
    别名
    METTL11A (METTL11A 产品)
    别名
    C9orf32 Protein, C11H9orf32 Protein, METTL11A Protein, NTM1A Protein, AD-003 Protein, HOMT1A Protein, NRMT Protein, 2610205E22Rik Protein, AL033331 Protein, AL033332 Protein, Mettl11a Protein, RGD1306582 Protein, mettl11a Protein, zgc:77488 Protein, N-terminal Xaa-Pro-Lys N-methyltransferase 1 Protein, NTMT1 Protein, Ntmt1 Protein, ntmt1 Protein
    背景

    Background: Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Methylation often occurs on nucleic bases in DNA or amino acids in protein structures. Methytransferase uses a reactive methyl group bound to sulfur in S-adenosyl methionine (SAM) as the methyl donor. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. This methylation occurs on cytosine residues. DNA methylation may be necessary for normal growth from embryonic stages in mammals. Methylation can serve to protect DNA from enzymatic cleavage, since restriction enzymes are unable to bind and recognize externally modified sequences. This is especially useful in bacterial restriction modification systems which use restriction enzymes to cleave foreign DNA while keeping their own DNA protected by methylation. Methylation of amino acids in the formation of proteins leads to more diversity of possible amino acids and therefore more diversity of function. The methylation reaction occurs on nitrogen atoms either on the N terminus or side-chain position of the protein and are usually irreversible.

    Synonym: AD-003,C9orf32,HOMT1A,METTL11A,NRMT,NTM1A

    分子量
    25.5 kDa
    NCBI登录号
    NP_054783
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