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METTL11A Protein (AA 1-223, full length) (His-SUMO Tag)

METTL11A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711881
发货至: 中国
  • 抗原 See all METTL11A 蛋白
    METTL11A (Methyltransferase Like 11A (METTL11A))
    蛋白类型
    Recombinant
    产品特性
    full length, AA 1-223
    宿主
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
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    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This METTL11A protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MTSEVIEDEK QFYSKAKTYW KQIPPTVDGM LGGYGHISSI DINSSRKFLQ RFLREGPNKT GTSCALDCGA GIGRITKRLL LPLFREVDMV DITEDFLVQA KTYLGEEGKR VRNYFCCGLQ DFTPEPDSYD VIWIQWVIGH LTDQHLAEFL RRCKGSLRPN GIIVIKDNMA QEGVILDDVD SSVCRDLDVV RRIICSAGLS LLAEERQENL PDEIYHVYSF ALR
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product METTL11A 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    METTL11A (Methyltransferase Like 11A (METTL11A))
    别名
    NTM1A (METTL11A 产品)
    别名
    C9orf32 Protein, C11H9orf32 Protein, METTL11A Protein, NTM1A Protein, AD-003 Protein, HOMT1A Protein, NRMT Protein, 2610205E22Rik Protein, AL033331 Protein, AL033332 Protein, Mettl11a Protein, RGD1306582 Protein, mettl11a Protein, zgc:77488 Protein, N-terminal Xaa-Pro-Lys N-methyltransferase 1 Protein, NTMT1 Protein, Ntmt1 Protein, ntmt1 Protein
    背景
    Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
    分子量
    41.4 kDa
    UniProt
    Q9BV86
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