Quick Overview for MBL2 蛋白 (ABIN7320615)
抗原
See all MBL2 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Mouse MBL2/MBP-C Protein
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序列
- Glu19-Asp244
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产品特性
- Recombinant Mouse Mannose Binding Lectin 2 is produced by our Mammalian expression system and the target gene encoding Glu19-Asp244 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) protein (His tag)
MBL2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) (AA 130-248) (Active) protein (His tag,GST tag)MBL2 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
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别名
- MBL2/MBP-C
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背景
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Background: Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.
Synonym: Mannose binding lectin (C), isoform CRA_b, Mannose-binding protein C, Mbl2, MBL-2, Mannose Binding Lectin 2
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分子量
- 24.0 kDa
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UniProt
- Q3UEK1
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途径
- Complement System, Positive Regulation of Immune Effector Process
抗原
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