产品编号 ABIN7320615
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for MBL2 Protein (AA 19-244) (ABIN7320615)
抗原
See all MBL2 蛋白
MBL2
(Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 90 % as determined by reducing SDS-PAGE.
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产品特性
- AA 19-244
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原理
- Recombinant Mouse MBL2/MBP-C Protein
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序列
- Glu19-Asp244
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产品特性
- Recombinant Mouse Mannose Binding Lectin 2 is produced by our Mammalian expression system and the target gene encoding Glu19-Asp244 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) (AA 19-244) protein (His tag)
MBL2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
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别名
- MBL2/MBP-C
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背景
- MBL-2,Mannose Binding Lectin 2,Mannose binding lectin (C),Mannose-binding protein C,Mbl2,isoform CRA_b,Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.
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分子量
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Calculated MW: 24.0 kDa
Observed MW: 28 kDa
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UniProt
- Q3UEK1
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途径
- Complement System, Positive Regulation of Immune Effector Process
抗原
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