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Lactoferrin Protein (His tag)

This Recombinant Lactoferrin protein is expressed in HEK-293 Cells.
产品编号 ABIN7320159
发货至: 中国

Quick Overview for Lactoferrin Protein (His tag) (ABIN7320159)

抗原

See all Lactoferrin (LTF) 蛋白
Lactoferrin (LTF) (Lactotransferrin (LTF))

蛋白类型

Recombinant

宿主

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小鼠

资源

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HEK-293 Cells

纯度

> 92 % as determined by SDS-PAGE
  • 标记

    This Lactoferrin protein is labelled with His tag.

    原理

    Recombinant Mouse Lactotransferrin/LTF Protein (His Tag)

    序列

    Met 1-Gln 707

    产品特性

    A DNA sequence encoding the mouse LTF (AAH06904.1) (Met 1-Gln 707) was expressed, with a C-terminal polyhistidine tag.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Lactoferrin (LTF) (Lactotransferrin (LTF))

    别名

    Lactotransferrin/LTF

    背景

    Background: Lactotransferrin, also known as Lactoferrin, Talalactoferrin and LTF, is a secreted protein which belongs to the transferrin family. Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Lactoferrin / LTF is a globular glycoprotein that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin / LTF is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin / LTF can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk. Lactoferrin / LTF is one of the components of the immune system of the body, it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterial activity to human infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.

    Synonym: Csp82,Lf,MMS10R,Ms10r

    分子量

    77.2 kDa

    途径

    Transition Metal Ion Homeostasis
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