Kallikrein 2 Protein (KLK2) (His tag)
Quick Overview for Kallikrein 2 Protein (KLK2) (His tag) (ABIN7318697)
抗原
See all Kallikrein 2 (KLK2) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Kallikrein 2 protein is labelled with His tag.
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原理
- Recombinant Human Kallikrein 2/KLK2 Protein (His Tag)
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序列
- Pro19-Pro261
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产品特性
- Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 150 mM NaCl, pH 3.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Kallikrein 2 (KLK2)
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别名
- Kallikrein 2/KLK2
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背景
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Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.
Synonym: Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2
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分子量
- 27.9 kDa
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UniProt
- P20151
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途径
- Complement System
抗原
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