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Kallikrein 2 Protein (KLK2) (His tag)

This Recombinant Kallikrein 2 protein is expressed in 人细胞.
产品编号 ABIN7318697
发货至: 中国

Quick Overview for Kallikrein 2 Protein (KLK2) (His tag) (ABIN7318697)

抗原

See all Kallikrein 2 (KLK2) 蛋白
Kallikrein 2 (KLK2)

蛋白类型

Recombinant

宿主

  • 10
  • 1
  • 1

资源

  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This Kallikrein 2 protein is labelled with His tag.

    原理

    Recombinant Human Kallikrein 2/KLK2 Protein (His Tag)

    序列

    Pro19-Pro261

    产品特性

    Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 150 mM NaCl, pH 3.5.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    Kallikrein 2 (KLK2)

    别名

    Kallikrein 2/KLK2

    背景

    Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

    Synonym: Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2

    分子量

    27.9 kDa

    UniProt

    P20151

    途径

    Complement System
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