Kallikrein 1 Protein (KLK1) (His tag)
Quick Overview for Kallikrein 1 Protein (KLK1) (His tag) (ABIN7320811)
抗原
See all Kallikrein 1 (KLK1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Kallikrein 1 protein is labelled with His tag.
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原理
- Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)
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序列
- Pro19-Asp261
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产品特性
- Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Kallikrein 1 (KLK1)
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别名
- Kallikrein 1/KLK1
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背景
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Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.
Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6
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分子量
- 27.9 kDa
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UniProt
- P15947
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途径
- Complement System
抗原
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