JAG1 Protein (Fc Tag)
Quick Overview for JAG1 Protein (Fc Tag) (ABIN7319310)
抗原
See all JAG1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This JAG1 protein is labelled with Fc Tag.
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原理
- Recombinant Human Jagged 1/JAG1 Protein (Fc Tag)
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序列
- Gln34-Ser1046
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产品特性
- Recombinant Human jagged-1 is produced by our Mammalian expression system and the target gene encoding Gln34-Ser1046 is expressed with a Fc tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Jagged 1 (JAG1) (AA 37-119) protein (GST tag)
JAG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 531-620) protein (GST tag)JAG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 1-1067) (Active) protein (Fc Tag)JAG1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- JAG1 (Jagged 1 (JAG1))
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别名
- Jagged 1/JAG1
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背景
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Background: Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations.
Synonym: Protein jagged-1 I, Jagged-1, JAGL1, HJ1, JAG1 and CD339,AGS,AHD,AWS,Jagged 1
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分子量
- 138.5 kDa
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NCBI登录号
- NP_000205
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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