IL12B Protein (AA 23-328)
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北京 101111
Quick Overview for IL12B Protein (AA 23-328) (ABIN7318099)
抗原
See all IL12B 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 23-328
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原理
- Recombinant Human IL-12 p40/IL-12B Protein
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序列
- Ile23-Ser328
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产品特性
- Recombinant Human Interleukin-12 subunit beta is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Interleukin 12 beta (IL12B) (AA 23-328) (Active) protein (His tag)
IL12B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 12 beta (IL12B) (AA 229-328) protein (GST tag)IL12B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Interleukin 12 beta (IL12B) (AA 23-335) protein (His tag)IL12B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 12 beta (IL12B) (AA 23-327), (full length) protein (His tag)IL12B 宿主: 绵羊 宿主: 酵母菌 Recombinant > 90 % ELISA
Interleukin 12 beta (IL12B) (AA 23-328), (full length) protein (GST tag)IL12B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Interleukin 12 beta (IL12B) (AA 23-328) protein (Fc Tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL12B (Interleukin 12 beta (IL12B))
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别名
- IL-12 p40/IL-12B
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背景
- IL-12/IL-23 p,IL-12 subunit p,NK cell stimulatory factor chain,NK cell Stimulating Factor Chain,CLMF p,IMD,IL12B,CLMF,CLMF2,IL-12B,IMD28,IMD29,NKSF,NKSF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40),IL-12/IL-23 p40,NK cell Stimulating Factor Chain 2,p40,Interleukin-12 subunit beta,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,IL 12B,IL12 p40,Interleukin 12 beta chain,Interleukin 12 p40,Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
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分子量
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Calculated MW: 34.6 kDa
Observed MW: 40-47 kDa
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基因ID
- 3593
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UniProt
- P29460
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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