IL-11 Protein (AA 23-199)
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北京 101111
Quick Overview for IL-11 Protein (AA 23-199) (ABIN7319568)
抗原
See all IL-11 (IL11) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 23-199
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原理
- Recombinant Human Interleukin-11/IL-11 Protein
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序列
- Gly23-Leu199
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产品特性
- Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- Interleukin-11/IL-11
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背景
- Interleukin,Adipogenesis Inhibitory Factor,AGIF,AGIF (Adipogenesis Inhibitory Factor),IL-11,Interleukin-11,Oprelvekin,IL11,Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
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分子量
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Calculated MW: 19.0 kDa
Observed MW: 19 kDa
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基因ID
- 3589
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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