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IL-11 蛋白

This Recombinant IL-11 protein is expressed in Yeast (Pichia pastoris).
产品编号 ABIN7319568
发货至: 中国

Quick Overview for IL-11 蛋白 (ABIN7319568)

抗原

See all IL-11 (IL11) 蛋白
IL-11 (IL11) (Interleukin 11 (IL11))

蛋白类型

Recombinant

宿主

  • 16
  • 11
  • 2
  • 2

资源

  • 14
  • 7
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Yeast (Pichia pastoris)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Interleukin-11/IL-11 Protein

    序列

    Gly23-Leu199

    产品特性

    Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-11 (IL11) (Interleukin 11 (IL11))

    别名

    Interleukin-11/IL-11

    背景

    Background: Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Synonym: Interleukin-11, IL-11, Adipogenesis Inhibitory Factor, AGIF, Oprelvekin, IL11

    分子量

    19 kDa

    UniProt

    P20809

    途径

    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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