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IMPA2 Protein (His tag)

This Recombinant IMPA2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318621
发货至: 中国

Quick Overview for IMPA2 Protein (His tag) (ABIN7318621)

抗原

See all IMPA2 蛋白
IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))

蛋白类型

Recombinant

宿主

  • 6
  • 2
  • 1
  • 1

资源

  • 3
  • 2
  • 2
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This IMPA2 protein is labelled with His tag.

    原理

    Recombinant Human IMPA2/IMPase 2 Protein (His Tag)

    序列

    Met 1-Lys288

    产品特性

    Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 106,314.67 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 2 mM DTT, pH 8.0.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))

    别名

    IMPA2/IMPase 2

    背景

    Background: Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

    Synonym: Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P

    分子量

    33.5 kDa

    UniProt

    O14732
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