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HMBS Protein (His tag)

This Recombinant HMBS protein is expressed in 人细胞.
产品编号 ABIN7318923
发货至: 中国

Quick Overview for HMBS Protein (His tag) (ABIN7318923)

抗原

See all HMBS 蛋白
HMBS (Hydroxymethylbilane Synthase (HMBS))

蛋白类型

Recombinant

宿主

  • 8
  • 1
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资源

  • 4
  • 2
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  • 1
人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This HMBS protein is labelled with His tag.

    原理

    Recombinant Human HMBS Protein (His Tag)

    序列

    Ser2-His361

    产品特性

    Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    HMBS (Hydroxymethylbilane Synthase (HMBS))

    别名

    HMBS

    背景

    Background: Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.

    Synonym: Porphobilinogen Deaminase, PBG-D, Hydroxymethylbilane Synthase, HMBS, Pre-Uroporphyrinogen Synthase, HMBS, PBGD, UPS

    分子量

    40.5 kDa

    UniProt

    P08397
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