Quick Overview for CD74 Protein (His tag) (ABIN7320753)
抗原
See all CD74 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This CD74 protein is labelled with His tag.
-
原理
- Recombinant Mouse CD74 Protein (His Tag)
-
序列
- Gln56-Leu215
-
产品特性
- Recombinant Mouse HLA class II histocompatibility antigen gamma chain is produced by our Mammalian expression system and the target gene encoding Gln56-Leu215 is expressed with a 6His tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Mouse价格从 146,137.28 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
HLA-DR-gamma (CD74) (AA 1-296) protein (His tag)
custom-made CD74 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
HLA-DR-gamma (CD74) (AA 1-279) protein (His tag)custom-made CD74 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
HLA-DR-gamma (CD74) (AA 56-279) protein (His tag)CD74 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA-DR-gamma (CD74) (AA 1-160) protein (GST tag)CD74 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HLA-DR-gamma (CD74) protein (His tag,mFc Tag)CD74 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
HLA-DR-gamma (CD74) (AA 73-232) protein (His tag)CD74 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
HLA-DR-gamma (CD74) protein (Fc Tag)CD74 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- CD74 (HLA-DR-gamma (CD74))
-
别名
- CD74
-
背景
-
Background: Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane glycoprotein which contains 1 thyroglobulin type-1 domain. Mouse CD74 shares 75 % and 88 % aa sequence identity with human and rat CD74, respectively. CD74 plays an important role in adaptive immunity, inflammation, and cancer. It plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.CD74 also associates with CD44 and binds with high affinity to the cytokine MIF, leading to inflammatory leukocyte responses, protection from tissue fibrosis, B cell proliferative and survival signaling, and the up-regulation of angiogenic factors in endometrial stromal cells.
Synonym: Cluster of Differentiation 74,CD74 antigen, CD74 Molecule, major histocompatibility complex, class II invariant chain, DHLAG gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, MHC HLA-DR gamma chain, CD74, DHLAG, HLADG, Ia-gamma, INVG34,
-
分子量
- 19.4 kDa
-
途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
抗原
-
