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Quick Overview for GZMB Protein (His tag) (ABIN7320540)
抗原
See all GZMB 蛋白蛋白类型
宿主
资源
纯度
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标记
- This GZMB protein is labelled with His tag.
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原理
- Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)
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序列
- Gly19-Ser247
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产品特性
- Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Granzyme B (GZMB) (AA 21-247) protein (GST tag)
GZMB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 148-247) protein (GST tag)GZMB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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别名
- Granzyme B/GZMB
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背景
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Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1
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分子量
- 26.5 kDa
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UniProt
- P04187
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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