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GZMB Protein (His tag)

This Recombinant GZMB protein is expressed in 人细胞.
产品编号 ABIN7320540
发货至: 中国

Quick Overview for GZMB Protein (His tag) (ABIN7320540)

抗原

See all GZMB 蛋白
GZMB (Granzyme B (GZMB))

蛋白类型

Recombinant

宿主

  • 10
  • 6
  • 3
  • 1
  • 1
小鼠

资源

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人细胞

纯度

> 85 % as determined by SDS-PAGE
  • 标记

    This GZMB protein is labelled with His tag.

    原理

    Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

    序列

    Gly19-Ser247

    产品特性

    Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B/GZMB

    背景

    Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1

    分子量

    26.5 kDa

    UniProt

    P04187

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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