Glutathione Synthetase Protein (GSS) (His tag)
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北京 101111
Quick Overview for Glutathione Synthetase Protein (GSS) (His tag) (ABIN7318542)
抗原
See all Glutathione Synthetase (GSS) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Glutathione Synthetase protein is labelled with His tag.
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原理
- Recombinant Human GSS Protein (His Tag)
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序列
- Ala2-Val474
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产品特性
- Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Glutathione Synthetase (GSS)
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别名
- GSS
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背景
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Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.
Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS
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分子量
- 53.5 kDa
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UniProt
- P48637
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途径
- Warburg Effect
抗原
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