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Glutathione Synthetase Protein (GSS) (His tag)

This Recombinant Glutathione Synthetase protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318542
发货至: 中国

Quick Overview for Glutathione Synthetase Protein (GSS) (His tag) (ABIN7318542)

抗原

See all Glutathione Synthetase (GSS) 蛋白
Glutathione Synthetase (GSS)

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This Glutathione Synthetase protein is labelled with His tag.

    原理

    Recombinant Human GSS Protein (His Tag)

    序列

    Ala2-Val474

    产品特性

    Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    Glutathione Synthetase (GSS)

    别名

    GSS

    背景

    Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

    Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

    分子量

    53.5 kDa

    UniProt

    P48637

    途径

    Warburg Effect
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