GSTP1 蛋白
Our Local Distributor
北京 101111
Quick Overview for GSTP1 蛋白 (ABIN7318541)
抗原
See all GSTP1 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human GSTP1 Protein
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序列
- Met 1-Glu210
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产品特性
- Recombinant Human Glutathione S-Transferase pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Glu210 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
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别名
- GSTP1
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背景
- FAEES3,GST class-pi,GST3,GSTP1,GSTP1-1,Glutathione S-transferase P,Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
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分子量
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Calculated MW: 23.5 kDa
Observed MW: 22-25 kDa
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基因ID
- 2950
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UniProt
- P09211
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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