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GSTP1 蛋白

This Recombinant GSTP1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318541
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSTP1 蛋白 (ABIN7318541)

抗原

See all GSTP1 蛋白
GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human GSTP1 Protein

    序列

    Met 1-Glu210

    产品特性

    Recombinant Human Glutathione S-Transferase pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Glu210 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

    别名

    GSTP1

    背景

    FAEES3,GST class-pi,GST3,GSTP1,GSTP1-1,Glutathione S-transferase P,Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

    分子量

    Calculated MW: 23.5 kDa

    Observed MW: 22-25 kDa

    基因ID

    2950

    UniProt

    P09211

    途径

    Cellular Response to Molecule of Bacterial Origin
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