GNS Protein (His tag)
Quick Overview for GNS Protein (His tag) (ABIN7318800)
抗原
See all GNS 蛋白蛋白类型
宿主
资源
纯度
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标记
- This GNS protein is labelled with His tag.
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原理
- Recombinant Human GNS Protein (His Tag)
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序列
- Val37-Leu552
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产品特性
- Recombinant Human N-Acetylglucosamine-6-Sulfatase is produced by our Mammalian expression system and the target gene encoding Val37-Leu552 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) protein (GST tag)
GNS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Glucosamine (N-Acetyl)-6-Sulfatase (GNS) protein (Myc-DYKDDDDK Tag)GNS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl,10 % Glycerol, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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别名
- GNS
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背景
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Background: N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase hydrolyzes the 6-Sulfate groups of the N-Acetyl-D-Glucosamine 6-Sulfate units of Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase binds 1 Calcium ion per subunit. N-Acetylglucosamine-6-Sulfatase deficiency are the cause of Mucopolysaccharidosis Type 3D (MPS3D), an inborn error leading to lysosomal accumulation of heparan sulfate. MPS3D has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
Synonym: N-Acetylglucosamine-6-Sulfatase, Glucosamine-6-Sulfatase, G6S, GNS
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分子量
- 59.4 kDa
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UniProt
- P15586
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途径
- Glycosaminoglycan Metabolic Process
抗原
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