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FRZB Protein (His tag)

FRZB 宿主: 人 宿主: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317893
发货至: 中国
  • 抗原 See all FRZB 蛋白
    FRZB (Frizzled-Related Protein (FRZB))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 2
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    HEK-293 Cells
    标记
    This FRZB protein is labelled with His tag.
    原理
    Recombinant Human FRZB/sFRP-3 Protein (His Tag)
    序列
    Ala32-Asn325
    产品特性
    A DNA sequence encoding the human FRZB (NP_001454.2) (Ala32-Asn325) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FRZB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    FRZB (Frizzled-Related Protein (FRZB))
    别名
    FRZB/sFRP-3 (FRZB 产品)
    别名
    Frp Protein, Sfrp3 Protein, frezzled Protein, fritz Protein, frzb-1 Protein, FRE Protein, FRITZ Protein, FRP-3 Protein, FRZB-1 Protein, FRZB-PEN Protein, FRZB1 Protein, FZRB Protein, OS1 Protein, SFRP3 Protein, SRFP3 Protein, hFIZ Protein, Frzb-1 Protein, frizzled-related protein Protein, Frzb Protein, FRZB Protein
    背景

    Background: FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis (OA) susceptibility. FRZB may serve an important role in determining hip shape and may modify the relationship between hip shape and OA.

    Synonym: FRE,FRITZ,FRP-3,FRZB-1,FRZB-PEN,FRZB1,FZRB,hFIZ,OS1,SFRP3,SRFP3

    分子量
    34.5 kDa
    NCBI登录号
    NP_001454
    途径
    WNT signaling, Positive Regulation of fat Cell Differentiation
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