FRZB Protein (His tag)
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Quick Overview for FRZB Protein (His tag) (ABIN7317893)
抗原
See all FRZB 蛋白蛋白类型
宿主
资源
纯度
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标记
- This FRZB protein is labelled with His tag.
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原理
- Recombinant Human FRZB/sFRP-3 Protein (His Tag)
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序列
- Ala32-Asn325
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产品特性
- A DNA sequence encoding the human FRZB (NP_001454.2) (Ala32-Asn325) was expressed with a C-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Frizzled-Related Protein (FRZB) protein
FRZB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
Frizzled-Related Protein (FRZB) (AA 39-760) protein (GST tag)FRZB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- FRZB (Frizzled-Related Protein (FRZB))
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别名
- FRZB/sFRP-3
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背景
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Background: FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis (OA) susceptibility. FRZB may serve an important role in determining hip shape and may modify the relationship between hip shape and OA.
Synonym: FRE,FRITZ,FRP-3,FRZB-1,FRZB-PEN,FRZB1,FZRB,hFIZ,OS1,SFRP3,SRFP3
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分子量
- 34.5 kDa
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NCBI登录号
- NP_001454
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途径
- WNT signaling, Positive Regulation of fat Cell Differentiation
抗原
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