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FGF7 蛋白

This Recombinant FGF7 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318490
发货至: 中国

Quick Overview for FGF7 蛋白 (ABIN7318490)

抗原

See all FGF7 蛋白
FGF7 (Fibroblast Growth Factor 7 (FGF7))

蛋白类型

Recombinant

生物活性

Active

宿主

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human FGF-7/KGF Protein (Active)

    序列

    Cys32-Thr194

    产品特性

    Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our E.coli expression system and the target gene encoding Cys32-Thr194 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Human KGF at 2μg/ml(100 μl/well) can bind Human FGF R3-Fc(Cat: PKSH033678). The ED50 of Human KGF is 0.788 ug/ml .
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, pH 8.0,l50 mM NaCl.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    FGF7 (Fibroblast Growth Factor 7 (FGF7))

    别名

    FGF-7/KGF

    背景

    Background: Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

    Synonym: Fibroblast growth factor 7,FGF-7,Heparin-binding growth factor 7,HBGF-7,Keratinocyte growth factor,FGF7,KGF

    分子量

    19.1 kDa

    UniProt

    P21781

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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