FETUB Protein (His tag)
Quick Overview for FETUB Protein (His tag) (ABIN7318470)
抗原
See all FETUB 蛋白蛋白类型
宿主
资源
纯度
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标记
- This FETUB protein is labelled with His tag.
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原理
- Recombinant Human Fetuin-B/FETUB Protein (His Tag)
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序列
- Cys16-Pro382
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产品特性
- Recombinant Human Fetuin B is produced by our Mammalian expression system and the target gene encoding Cys16-Pro382 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Fetuin B (FETUB) (AA 177-382) protein (His-IF2DI Tag)
FETUB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Fetuin B (FETUB) (AA 1-382) protein (GST tag)FETUB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fetuin B (FETUB) protein (His tag)FETUB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- FETUB (Fetuin B (FETUB))
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别名
- Fetuin-B/FETUB
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背景
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Background: Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20 % amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
Synonym: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB
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分子量
- 41.5 kDa
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UniProt
- Q9UGM5
抗原
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