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FETUB Protein (His tag)

This Recombinant FETUB protein is expressed in 人细胞.
产品编号 ABIN7318470
发货至: 中国
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Quick Overview for FETUB Protein (His tag) (ABIN7318470)

抗原

See all FETUB 蛋白
FETUB (Fetuin B (FETUB))

蛋白类型

Recombinant

宿主

  • 8
  • 5
  • 4
  • 3

资源

  • 10
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This FETUB protein is labelled with His tag.

    原理

    Recombinant Human Fetuin-B/FETUB Protein (His Tag)

    序列

    Cys16-Pro382

    产品特性

    Recombinant Human Fetuin B is produced by our Mammalian expression system and the target gene encoding Cys16-Pro382 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    FETUB (Fetuin B (FETUB))

    别名

    Fetuin-B/FETUB

    背景

    Background: Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20 % amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.

    Synonym: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB

    分子量

    41.5 kDa

    UniProt

    Q9UGM5
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