EPH Receptor A3 Protein (EPHA3) (AA 569-984) (His-GST)
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Quick Overview for EPH Receptor A3 Protein (EPHA3) (AA 569-984) (His-GST) (ABIN7319998)
抗原
See all EPH Receptor A3 (EPHA3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 569-984
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标记
- This EPH Receptor A3 protein is labelled with His-GST.
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原理
- Recombinant Mouse EphA3 Protein (aa 569-984, His & GST Tag)
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序列
- Gly569-Val984
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产品特性
- A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Kinase activity untested
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- EPH Receptor A3 (EPHA3)
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别名
- EphA3
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背景
- AW492086,Cek4,ETK1,End3,Hek,Hek4,Mek4,Tyro4,EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
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分子量
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Calculated MW: 74.3 kDa
Observed MW: 66 kDa
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途径
- RTK signaling, Regulation of Cell Size
抗原
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