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DCLK1 蛋白

This Recombinant DCLK1 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7317531
发货至: 中国

Quick Overview for DCLK1 蛋白 (ABIN7317531)

抗原

See all DCLK1 蛋白
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

蛋白类型

Recombinant

宿主

  • 9
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资源

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Baculovirus infected Insect Cells

纯度

> 80 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human DCAMKL1 Protein

    序列

    Met 1-Val 705

    产品特性

    A DNA sequence encoding the human DCLK1 (O15075-1) (Met 1-Val 705) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
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    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    DCAMKL1

    背景

    Background: DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Its microtubule-polymerizing activity is independent of its protein kinase activity. DCAMKL1 may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It may also participate in functions of the mature nervous system.

    Synonym: CL1,CLICK1,DCAMKL1,DCDC3A,DCLK

    分子量

    78.5 kDa
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