Cytochrome C Protein (His tag)
Quick Overview for Cytochrome C Protein (His tag) (ABIN7318387)
抗原
See all Cytochrome C (CYCS) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cytochrome C protein is labelled with His tag.
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原理
- Recombinant Human Cytochrome C/CYCS Protein (His Tag)
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序列
- Gly2-Glu105
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产品特性
- Recombinant Human Cytochrome C is produced by our E.coli expression system and the target gene encoding Gly2-Glu105 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Cytochrome C, Somatic (CYCS) (AA 1-105) protein (His tag)
CYCS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cytochrome C, Somatic (CYCS) (AA 1-105) protein (GST tag)CYCS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cytochrome C, Somatic (CYCS) (AA 2-105) protein (GST tag)CYCS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Cytochrome C, Somatic (CYCS) protein (Myc-DYKDDDDK Tag)CYCS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.15M NaCl, 20 % Glycerol, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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别名
- Cytochrome C/CYCS
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背景
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Background: Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Synonym: Cytochrome C, CYCS, CYC
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分子量
- 12.8 kDa
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UniProt
- P99999
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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