CST7 蛋白
Quick Overview for CST7 蛋白 (ABIN7195341)
抗原
See all CST7 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human Cystatin 7/CST7 Protein
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序列
- Met 1-His 145
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产品特性
- The mature form of the human Cystatin F (NP_003641.3) (Met 1-His 145) with five amino acids (DDDDK) at the C-terminus was expressed and purified.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Cystatin F (Leukocystatin) (CST7) protein (His tag)
CST7 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cystatin F (Leukocystatin) (CST7) (Active) protein (Fc Tag)CST7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE Active
Cystatin F (Leukocystatin) (CST7) (AA 1-167) protein (GST tag)CST7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CST7 (Cystatin F (Leukocystatin) (CST7))
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别名
- Cystatin 7/CST7
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背景
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Background: The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.
Synonym: Cystatin-F, Cystatin-7, Cystatin-Like Metastasis-Associated Protein, CMAP, Leukocystatin, CST7
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分子量
- 15.2 kDa
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NCBI登录号
- NP_003641
抗原
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