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C3 蛋白

C3 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320494
发货至: 中国
  • 抗原 See all C3 蛋白
    C3 (Complement Component 3 (C3))
    蛋白类型
    Recombinant
    宿主
    • 22
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 24
    • 13
    • 8
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Mouse Complement Component C3a/C3a Protein
    序列
    Ser671-Arg748
    产品特性
    Recombinant Mouse Complement Component C3a is produced by our E.coli expression system and the target gene encoding Ser671-Arg748 is expressed.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product C3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    C3 (Complement Component 3 (C3))
    别名
    Complement Component C3a/C3a (C3 产品)
    别名
    AHUS5 Protein, ARMD9 Protein, ASP Protein, C3a Protein, C3b Protein, CPAMD1 Protein, AI255234 Protein, HSE-MSF Protein, Plp Protein, C3 Protein, C3-1 Protein, sb:cb26 Protein, si:dkey-76b14.4 Protein, wu:fi34b03 Protein, wu:fj86e11 Protein, C3d Protein, asp Protein, cpamd1 Protein, c3 Protein, complement C3 Protein, complement component 3 Protein, complement component c3a, duplicate 1 Protein, complement component 3 L homeolog Protein, complement component C3 Protein, complement C3-like Protein, C3 Protein, c3a.1 Protein, c3.L Protein, LOC443475 Protein, c3 Protein, c3-1 Protein, LOC100060539 Protein
    背景

    Background: Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.

    Synonym: Complement Component C3a, Anaphylatoxin, C3a

    分子量
    9.2 kDa
    UniProt
    P01027
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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