C3 Protein (AA 672-748)
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北京 101111
Quick Overview for C3 Protein (AA 672-748) (ABIN7318326)
抗原
See all C3 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 672-748
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原理
- Recombinant Human Complement Component C3a/C3a Protein
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序列
- Ser672-Arg748
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产品特性
- Recombinant Human Complement Component C3a is produced by our E.coli expression system and the target gene encoding Ser672-Arg748 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Complement Component 3 (C3) (AA 23-1663) (Active) protein (His tag)
C3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Complement Component 3 (C3) (AA 25-1663) (Active) protein (His tag)C3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Complement Component 3 (C3) (AA 1534-1644) protein (GST tag)C3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Complement Component 3 (C3) (AA 671-748) proteinC3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- C3 (Complement Component 3 (C3))
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别名
- Complement Component C3a/C3a
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背景
- Anaphylatoxin,C3a,Complement Component C3a,Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.
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分子量
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Calculated MW: 9.1 kDa
Observed MW: 13 kDa
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基因ID
- 718
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UniProt
- P01024
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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