Clusterin Protein (CLU) (His tag)
Quick Overview for Clusterin Protein (CLU) (His tag) (ABIN7320262)
抗原
See all Clusterin (CLU) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Clusterin protein is labelled with His tag.
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原理
- Recombinant Mouse Clusterin/ApoJ Protein (His Tag)
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序列
- Met 1-Glu 448
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产品特性
- A DNA sequence encoding the mouse CLU (NP_038520.2) (Met 1-Glu 448) was expressed, with a C-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Clusterin (CLU) (AA 184-293) protein (His-IF2DI Tag)
CLU 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Clusterin (CLU) (AA 23-449) protein (His-IF2DI Tag)CLU 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Clusterin (CLU) (Active) protein (His tag)CLU 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Clusterin (CLU) (AA 402-501) protein (GST tag)CLU 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Clusterin (CLU) (AA 23-449) protein (His tag)CLU 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Clusterin (CLU)
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别名
- Clusterin/ApoJ
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背景
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Background: Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Synonym: Clusterin,Apolipoprotein J,Clustrin,Sulfated glycoprotein 2,ApoJ, Cli, D14Ucla3, Sgp-2, Sgp2, SP-40,Sugp-2
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分子量
- 50.8 kDa
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NCBI登录号
- NP_038520
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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