CDC37 蛋白
Quick Overview for CDC37 蛋白 (ABIN7195023)
抗原
See all CDC37 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Mouse CDC37/CDC37A Protein
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序列
- Met1-Ala379
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产品特性
- A DNA sequence encoding the mouse CDC37 (Q61081) (Met1-Ala379) was expressed with two additional amino acids (Gly & Pro) at the N-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Mouse价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Mouse价格从 152,621.24 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-379) protein (His tag)
custom-made CDC37 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) protein (His tag)custom-made CDC37 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) protein (GST tag)CDC37 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) proteinCDC37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) protein (GST tag,His tag)CDC37 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
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别名
- CDC37/CDC37A
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背景
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Background: CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is though to play an important role in the establishment of signaling pathways controlling cell proliferation through targeting intrinsically unstable oncoprotein kinases such as Cdk-4, Raf-1, and src to the molecular chaperone Hsp90. Decreased Hsp90 expression can reduce the levels of microtubule-associated protein tau, whose overexpression may induce many diseases. CDC37 is considered as a co-chaperone that is classified to Hsp90's accessory proteins. It has been reported that suppression of Cdc37 destabilized tau, leading to its clearance, whereas cdc37 overexpression preserved tau.Cdc37 was found to co-localize with tau in neuronal cells and to physically interact with tau from human brain. Moreover, Cdc37 levels significantly increased with age.
Synonym: p50,p50Cdc37
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分子量
- 44.7 kDa
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UniProt
- Q61081
抗原
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