CD86 Protein (CD86) (AA 29-247) (His tag)
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Quick Overview for CD86 Protein (CD86) (AA 29-247) (His tag) (ABIN7321266)
抗原
See all CD86 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 29-247
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标记
- This CD86 protein is labelled with His tag.
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原理
- Recombinant Rat CD86/B7-2 Protein (His Tag)
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序列
- Vla29-Lys247
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产品特性
- Recombinant Rat T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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CD86 (CD86) (AA 26-247) protein (Fc Tag)
CD86 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, AM, ADA
CD86 (CD86) (AA 26-247) (Active) protein (His-Avi Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD86 (CD86) (AA 25-239) (Active) protein (His tag)CD86 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 19-240) protein (His tag)HPLC verified CD86 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD86 (CD86) (AA 24-246) protein (His-DYKDDDDK-Strep II Tag)CD86 宿主: 人 宿主: HEK-293T Cells Recombinant WB, ELISA, SDS, PI
CD86 (CD86) (AA 26-247) (Active) protein (Biotin,His-Avi Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
CD86 (CD86) (AA 24-245) (Active) protein (Fc Tag)CD86 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag,AVI tag,Biotin)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 1-329) protein (GST tag)CD86 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD86
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别名
- CD86/B7-2
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背景
- Activation B7-2 antigen,B7-2,B7.2,B70,CD28LG2,CD86,LAB72,T-lymphocyte activation antigen CD86,T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
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分子量
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Calculated MW: 25.9 kDa
Observed MW: 35-55 kDa
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UniProt
- O35531
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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