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Quick Overview for CD84 Protein (CD84) (His tag) (ABIN7320706)
抗原
See all CD84 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD84 protein is labelled with His tag.
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原理
- Recombinant Mouse SLAMF5/CD84 Protein (His Tag)
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序列
- Lys22-Pro223
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产品特性
- Recombinant Mouse SLAM family member 5 is produced by our Mammalian expression system and the target gene encoding Lys22-Pro223 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD84 (CD84) (AA 22-225) protein (His-Avi Tag)
CD84 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD84 (CD84) (AA 22-225) protein (mFc-His Tag)CD84 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) (Active) protein (His tag)CD84 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD84 (CD84) (AA 22-225) protein (His tag)CD84 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS
CD84 (CD84) (AA 22-221) protein (Fc Tag)CD84 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD84
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别名
- SLAMF5/CD84
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背景
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Background: CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hematopoietic cell types, including monocytes, macrophages, dendritic cells, B lymphocytes, and platelets. Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation, which in turn enhances cell survival. Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.
Synonym: SLAM family member 5, Cd84, Leukocyte differentiation antigen CD84, Signaling lymphocytic activation molecule 5, CD84, Ly-9B, SLAMF5, CD84 antigen, CD84 Molecule, SLAM family member 5
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分子量
- 23.8 kDa
抗原
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