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CD70 Protein (mFc Tag)

This Recombinant CD70 protein is expressed in 人细胞.
产品编号 ABIN7319773
发货至: 中国

Quick Overview for CD70 Protein (mFc Tag) (ABIN7319773)

抗原

See all CD70 蛋白
CD70 (CD70 Molecule (CD70))

蛋白类型

Recombinant

宿主

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资源

  • 27
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人细胞

纯度

>95 % as determined by reducing SDS-PAGE.
  • 标记

    This CD70 protein is labelled with mFc Tag.

    原理

    Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)

    序列

    Gln45-Pro193

    产品特性

    Recombinant Human CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln45-Pro193 is expressed with a mFc tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD27 Ligand/TNFSF7/CD70

    背景

    Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64 % aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Synonym: CD70 antigen, CD70, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27LG, TNFSF7, CD27L

    分子量

    43 kDa

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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