CD58 Protein (CD58) (Fc Tag)
Quick Overview for CD58 Protein (CD58) (Fc Tag) (ABIN7317383)
抗原
See all CD58 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CD58 protein is labelled with Fc Tag.
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原理
- Recombinant Human LFA-3/CD58 Protein (Fc Tag)(Active)
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序列
- Met 1-Arg215
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产品特性
- A DNA sequence encoding the human CD58 (Q9BRW0) (Met1-Arg215) was expressed with the Fc region of human IgG1 at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA. Immobilized human CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 μg/ml.2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.10 μg/ml.
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CD58 (CD58) (AA 29-215) protein (Fc Tag)
CD58 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD58 (CD58) (AA 29-215) protein (His tag)CD58 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
CD58 (CD58) (AA 29-215) protein (His tag)CD58 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
CD58 (CD58) (AA 1-240) protein (GST tag)CD58 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD58 (CD58) (AA 29-215) protein (His tag)CD58 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD58 (CD58) (AA 29-215) (Active) protein (Fc Tag)CD58 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD58
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别名
- LFA-3/CD58
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背景
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Background: CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB; OBR
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分子量
- 48.5 kDa
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UniProt
- Q9BRW0
抗原
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