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CD5 Protein (CD5) (His tag)

This Recombinant CD5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7317688
发货至: 中国

Quick Overview for CD5 Protein (CD5) (His tag) (ABIN7317688)

抗原

See all CD5 蛋白
CD5

蛋白类型

Recombinant

生物活性

Active

宿主

  • 18
  • 5
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  • 1

资源

  • 18
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HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This CD5 protein is labelled with His tag.

    原理

    Recombinant Human CD5 Protein (His Tag)(Active)

    序列

    Met 1-Pro 372

    产品特性

    A DNA sequence encoding the human CD5 (NP_055022.2) extracellular domain (Met 1-Pro 372) was expressed with a polyhistidine tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to bind biotinylated recombinant human LCK in a functional ELISA.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD5

    别名

    CD5

    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.

    Synonym: LEU1,T1

    分子量

    40 kDa

    NCBI登录号

    NP_055022
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