CD4 Protein (CD4) (His tag)
Quick Overview for CD4 Protein (CD4) (His tag) (ABIN7319443)
抗原
See all CD4 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD4 protein is labelled with His tag.
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原理
- Recombinant Human CD4/LEU3 Protein (His Tag)
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序列
- Lys26-Trp390
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产品特性
- Recombinant Human CD4 is produced by our Mammalian expression system and the target gene encoding Lys26-Trp390 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD4 (CD4) (AA 26-390) protein (His-Avi Tag)
CD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD4 (CD4) (AA 26-390) protein (Fc Tag)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD4 (CD4) (AA 26-390) protein (His tag)CD4 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD4 (CD4) (AA 26-390) protein (His-Avi Tag,Biotin)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD4 (CD4) (AA 27-394) protein (His tag)CD4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD4 (CD4) (AA 26-390) (Active) protein (Fc Tag)CD4 宿主: 猕猴 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD4 (CD4) (AA 26-396) (Active) protein (Fc Tag)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD4 (CD4) (AA 26-390) (Active) protein (His tag)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD4 (CD4) (AA 26-396) (Active) protein (His tag,AVI tag,Biotin)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD4 (CD4) (AA 26-396) (Active) protein (Fc Tag,AVI tag,Biotin)CD4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD4
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别名
- CD4
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背景
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Background: CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations. Mature human CD4 consists of a 371 amino acid extracellular region containing four immunoglobulin-like domains, a 22 aa transmembrane segment, and a 40 aa cytoplasmic domain. CD4 is expressed along with CD8 on double positive T cells during their development in the thymus. CD4 binds directly to MHC class II molecules on antigen presenting cells (10). This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction. CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a co-receptor for the gp120 surface glycoprotein of HIV-1.
Synonym: T-cell surface glycoprotein CD4,T-cell surface antigen T4/Leu-3,CD4,Scd4,CD4mut
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分子量
- 41.7 kDa
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UniProt
- P01730
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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